Title :
Resting state functional near infrared spectroscopy
Author :
Rizzo-Sierra, Carlos V. ; Deepeshwar, Singh ; Kumar, Sudhakar ; Bhargav, Hemant ; Krishnamurthy, Mahesh ; Hongasandra, Nagendra R.
Author_Institution :
Unicolciencias, NeuroniKaS Lab., Colombia
fDate :
April 29 2013-May 4 2013
Abstract :
The present study investigated the spatial-temporal variation of oxygenated hemoglobin (HbO), deoxygenated hemoglobin (Hb), blood volume (BV) and blood oxygenation (BO) concentration changes in the prefrontal cortex, measured with functional near-infrared spectroscopy (fNIRS) during resting state. We examined 36 healthy right handed subjects seating with their minds and body quiet and still, as well as their eyes closed for 5 minutes. The spatial mean concentration change of the four estimated parameters across subjects was found near zero; Moreover, the mean concentration changes across subjects for HbO and Hb were found to be more reduced than those of BV and BO. In addition, there were no statistically voxelwise significant differences for the mean concentration changes related to HbO, Hb, BV, neither BO; This finding strongly suggests for a spatial stability in the mean concentration changes during resting state.
Keywords :
biomedical optical imaging; blood; brain; infrared imaging; oximetry; parameter estimation; proteins; spatiotemporal phenomena; BO; BV; HbO; blood oxygenation concentration; blood volume; deoxygenated hemoglobin; functional near-infrared spectroscopy; parameter estimation; prefrontal cortex; resting state functional; spatial mean concentration; spatial stability; spatial-temporal variation; time 5 min; Conferences; Couplings; IEEE catalog; Medical services; Brain oxygenation; Continuous wave; Functional near-infrared spectroscopy; MRS; Optical imaging;
Conference_Titel :
Health Care Exchanges (PAHCE), 2013 Pan American
Conference_Location :
Medellin
Print_ISBN :
978-1-4673-6254-2
DOI :
10.1109/PAHCE.2013.6568328
