Title :
Near Infrared Spectroscopy Differentiates Ligament and Tendon Composition
Author :
Padalkar, M. ; McGoverin, Cushla ; Pleshko, Nancy ; Barbash, S. ; Kropf, E.
Author_Institution :
Dept. of Bioeng., Temple Univ., Philadelphia, PA, USA
Abstract :
More than 200, 000 anterior cruciate ligament (ACL) tears occur in the United States each year, most in young healthy individuals. The torn ACL is generally either reconstructed with tendons. Ligamentization, or the transformation of a tendon graft to a healthy functional ligament, is poorly understood. Mid infrared (MIR) and near infrared (NIR) spectroscopy are sensitive to the chemical and structural changes in tissue and have been used to differentiate between normal and degenerated tissue. To date, the ability of both MIR and NIR spectroscopy to distinguish regional variations along the length of the ACL has not been explored.
Keywords :
biological tissues; biomedical optical imaging; infrared imaging; infrared spectroscopy; injuries; ACL; MIR spectroscopy; NIR spectroscopy; anterior cruciate ligament tears; chemical change; degenerated tissue; healthy functional ligament; ligament composition; ligamentization; mid infrared spectroscopy; near infrared spectroscopy; normal tissue; regional variation; structural change; tendon composition; tendon graft transformation; Educational institutions; Image reconstruction; Ligaments; Optical fibers; Principal component analysis; Spectroscopy; Tendons; Collagen and matrix composition; FTIR spectroscopy; Knee; Ligament and Tendon Biology; Proteoglycans;
Conference_Titel :
Bioengineering Conference (NEBEC), 2013 39th Annual Northeast
Conference_Location :
Syracuse, NY
Print_ISBN :
978-1-4673-4928-4
DOI :
10.1109/NEBEC.2013.121
