Near Infrared Spectroscopy Differentiates Ligament and Tendon Composition

Author

Padalkar, M. ; McGoverin, Cushla ; Pleshko, Nancy ; Barbash, S. ; Kropf, E.

Author_Institution

Dept. of Bioeng., Temple Univ., Philadelphia, PA, USA

fYear

2013

fDate

5-7 April 2013

Firstpage

66

Lastpage

67

Abstract

More than 200, 000 anterior cruciate ligament (ACL) tears occur in the United States each year, most in young healthy individuals. The torn ACL is generally either reconstructed with tendons. Ligamentization, or the transformation of a tendon graft to a healthy functional ligament, is poorly understood. Mid infrared (MIR) and near infrared (NIR) spectroscopy are sensitive to the chemical and structural changes in tissue and have been used to differentiate between normal and degenerated tissue. To date, the ability of both MIR and NIR spectroscopy to distinguish regional variations along the length of the ACL has not been explored.

Keywords

biological tissues; biomedical optical imaging; infrared imaging; infrared spectroscopy; injuries; ACL; MIR spectroscopy; NIR spectroscopy; anterior cruciate ligament tears; chemical change; degenerated tissue; healthy functional ligament; ligament composition; ligamentization; mid infrared spectroscopy; near infrared spectroscopy; normal tissue; regional variation; structural change; tendon composition; tendon graft transformation; Educational institutions; Image reconstruction; Ligaments; Optical fibers; Principal component analysis; Spectroscopy; Tendons; Collagen and matrix composition; FTIR spectroscopy; Knee; Ligament and Tendon Biology; Proteoglycans;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference (NEBEC), 2013 39th Annual Northeast

Conference_Location

Syracuse, NY

ISSN

2160-7001

Print_ISBN

978-1-4673-4928-4

Type

conf

DOI

10.1109/NEBEC.2013.121

Filename

6574360