Title :
Biocompatibility of CaO-Na2O-SiO2/TiO2 Glass Ceramic Scaffolds for Orthopaedic Applications
Author :
Wren, A.W. ; Coughlan, A. ; Smale, K.E. ; Misture, S.T. ; Mahon, B.P. ; Clarkin, O.M. ; Towler, Mark R.
Author_Institution :
Inamori Sch. of Eng., Alfred Univ., Alfred, NY, USA
Abstract :
This work aims to determine the effect of substituting TiO2for SiO2 in a 0.62SiO2-Na2O-0.24CaO based glass-ceramic scaffold. High temperature X-ray Diffraction (HT-XRD) was used to determine the sintering temperature (700°C). Both optical microscopy and x-ray micotomography was used to determine the average pore size (540-680μm) of each scaffold. Cytocompatibility of each scaffold was conducted using murine mesenchymal stem cells.
Keywords :
X-ray diffraction; biomedical materials; calcium compounds; cellular biophysics; glass ceramics; optical microscopy; orthopaedics; porosity; sintering; sodium compounds; tissue engineering; titanium compounds; CaO-Na2O-SiO2-TiO2; X-ray micotomography; XRD; biocompatibility; cytocompatibility; glass ceramic scaffolds; high temperature X-ray diffraction; murine mesenchymal stem cells; optical microscopy; orthopaedic applications; pore size; sintering temperature; temperature 700 degC; Ceramics; Glass; Microscopy; Optical diffraction; Stem cells; Temperature; Glass-ceramic scaffold; bioactive glass; porosity; stem cells;
Conference_Titel :
Bioengineering Conference (NEBEC), 2013 39th Annual Northeast
Conference_Location :
Syracuse, NY
Print_ISBN :
978-1-4673-4928-4
DOI :
10.1109/NEBEC.2013.56
