Assessment of Changes in Engineered Cartilage Using Infrared Spectroscopy and Mechanical Analysis

Author

Palukuru, Uday ; Shockley, Michael ; McGoverin, Cushla ; Glenn, Padraig ; Pleshko, Nancy ; Spencer, Richard H. ; Frank, Eibe ; Grodzinsky, Alan

Author_Institution

Bioeng. Dept., Temple Univ., Philadelphia, PA, USA

fYear

2013

fDate

5-7 April 2013

Firstpage

86

Lastpage

87

Abstract

Myriad tissue engineering approaches have been proposed to produce engineered cartilage but the resulting tissues generally lack the strength of native cartilage. Suboptimal matrix production may account for the observed lack of strength. Fourier Transform Infrared Imaging Spectroscopy (FT-IRIS) was used to assess the compositional changes in engineered cartilage to further understand the role of matrix formation in mechanics of engineered cartilage.

Keywords

Fourier transform spectra; biomechanics; biomedical optical imaging; infrared imaging; infrared spectra; mechanical strength; tissue engineering; Fourier transform infrared imaging spectroscopy; cartilage engineering; matrix formation; mechanical analysis; myriad tissue engineering; native cartilage; suboptimal matrix production; Biomedical engineering; Electronic mail; Electronics packaging; Production; Spectroscopy; Strain; Cartilage and matrix proteins; cartilage mechanics; spectroscopy; tissue engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference (NEBEC), 2013 39th Annual Northeast

Conference_Location

Syracuse, NY

ISSN

2160-7001

Print_ISBN

978-1-4673-4928-4

Type

conf

DOI

10.1109/NEBEC.2013.54

Filename

6574370