Title :
Peptide-Based Delivery System used for Tagging Syk Tyrosine Kinase Biomarker in Skin Cancer and Development of a Hyperspectral Imaging Device to Detect the Biomarker
Author :
Galligan, Bri ; Riling, Ryan ; Stufflet, Jessica ; Swarup, A. ; Sunkari, Chetana ; Alfego, David ; Kriete, Alicia
Author_Institution :
Sch. of Biomed. Eng., Drexel Univ. Philadelphia, Philadelphia, PA, USA
Abstract :
We propose to design a non-invasive diagnostic method for the early detection of SCC and BCC using a hyperspectral imaging device that will detect fluorescence. The technique used to deliver the fluorescent tag will be in the form of a topical formulation consisting of a Syk-specific peptide conjugated to a fluorescent dye encapsulated in liposomes.
Keywords :
biomedical optical imaging; cancer; dyes; fluorescence; skin; BCC detection; SCC detection; Syk tyrosine kinase biomarker tagging; biomarker detection; fluorescent dye; hyperspectral imaging device; liposomes; noninvasive diagnostic method; peptide based delivery system; skin cancer; Biomedical imaging; Fluorescence; Hyperspectral imaging; Peptides; Skin; Skin cancer; Spleen Tyrosine Kinase (Syk); hyperspectral imaging; liposomes; skin cancer; syk peptide;
Conference_Titel :
Bioengineering Conference (NEBEC), 2013 39th Annual Northeast
Conference_Location :
Syracuse, NY
Print_ISBN :
978-1-4673-4928-4
DOI :
10.1109/NEBEC.2013.125
