In-Line Detection Technology for Acoustophoretic Blood/Lipid Separation

Retransfusion of shed blood via cardiotomy suction during surgery causes complications due to the formation of lipid microemboli, which can lead to neurocognitive decline or disability. A system is being developed that uses acoustophoresis to separate lipids and red blood cells (RBCs) from a blood flow, thus allowing retransfusion of shed blood with reduced microemboli. In this work, an in-line detection technology is being developed to quantify the performance of the novel acoustophoretic blood/lipid separation system. The detection technology will use spectrophotometry to determine the concentration of RBCs and lipids trapped in the chamber, thus providing a measure of separation efficiency.