Title :
Comparing Structural Brain Connectivity by the Infinite Relational Model
Author :
Ambrosen, Karen Sando ; Herlau, Tue ; Dyrby, Tim ; Schmidt, Mikkel N. ; Morup, Morten
Author_Institution :
Dept. of Appl. Math. & Comput. Sci., Tech. Univ. of Denmark, Lyngby, Denmark
Abstract :
The growing focus in neuroimaging on analyzing brain connectivity calls for powerful and reliable statistical modeling tools. We examine the Infinite Relational Model (IRM) as a tool to identify and compare structure in brain connectivity graphs by contrasting its performance on graphs from the same subject versus graphs from different subjects. The inferred structure is most consistent between graphs from the same subject, however, the model is able to predict links in graphs from different subjects on par with results within a subject. The framework proposed can be used as a statistical modeling tool for the identification of structure and quantification of similarity in graphs of brain connectivity in general.
Keywords :
Bayes methods; biomedical imaging; statistical analysis; IRM tool; brain connectivity graph structure; graph similarity quantification; infinite relational model; link prediction; neuroimaging; nonparametric Bayesian generative model; statistical modeling tools; structural brain connectivity analysis; structure identification; Area measurement; Brain models; Complex networks; Imaging; Mutual information; Predictive models; Bayesian Methods; Neuroimaging; Relational Modelling; Structural Connectivity;
Conference_Titel :
Pattern Recognition in Neuroimaging (PRNI), 2013 International Workshop on
Conference_Location :
Philadelphia, PA
DOI :
10.1109/PRNI.2013.22