Title :
Synthesis of magnetic, macro/mesoporous bioactive glasses based on coral skeleton for bone tissue engineering
Author :
Chunhui Bian ; Huiming Lin ; Feng Zhang ; Jie Ma ; Fengxiao Li ; Xiaodan Wu ; Fengyu Qu
Author_Institution :
Dept. of Photoelectric Band Gap Mater., Harbin Normal Univ., Harbin, China
Abstract :
The magnetic and macro/mesoporous bioactive glasses scaffolds are synthesised successfully by the combination of coral and P123 as co-templates through an evaporation-induced self-assembly process. The prepared material can induce the precipitation of hydroxyapatite layers on their surface in SBF only within 12 h. At the same time, the material exhibited excellent super-paramagnetic and mechanical property. Furthermore, the biocompatible assessment confirmed that the obtained material presented the good biocompatibility and the enhanced adherence of HeLa cells. Herein, the novel materials are expected to have potential application for bone tissue engineering.
Keywords :
biomedical materials; bone; glass; porous materials; precipitation; self-assembly; superparamagnetism; tissue engineering; HeLa cells; P123; SBF surface; adherence; bioactive glass scaffolds; biocompatible assessment; bone tissue engineering; coral skeleton; evaporation-induced self-assembly process; hydroxyapatite layers; magnetic macroporous bioactive glasses; magnetic mesoporous bioactive glasses; precipitation; superparamagnetic property; synthesis; time 12 h;
Journal_Title :
Nanobiotechnology, IET
DOI :
10.1049/iet-nbt.2013.0056