Title :
Optimal control of crystallization of alpha-lactose monohydrate
Author :
Rachah, Amira ; Noll, Dominikus
Author_Institution :
Inst. de Math., Univ. de Toulouse, Toulouse, France
Abstract :
We present a mathematical model for solvated crystallization of a-lactose monohydrate in semi-batch mode. The process dynamics are governed by conservation laws including population, molar and energy balance equations. We present and discuss the model and then control the process with the goal to privilege the production of small particles in the range between 10-5 and 10-4μm. We compare several specific and unspecific cost functions leading to optimal strategies with significantly different effects on product quality. Control inputs are temperature, feed rate, and the choice of an appropriate crystal seed.
Keywords :
conservation laws; crystal growth from solution; crystallisation; mathematical analysis; organic compounds; solvation; α-lactose monohydrate; alpha-lactose monohydrate; conservation laws; crystal seed; energy balance equations; feed rate; mathematical model; molar equations; optimal crystallization control; population equations; process dynamics; product quality; semibatch mode; small particles production; solvated crystallization; specific cost functions; temperature inputs; unspecific cost functions; Crystallization; Feeds; Mathematical model; Sociology; Statistics; Temperature control;
Conference_Titel :
Control Conference (ASCC), 2013 9th Asian
Conference_Location :
Istanbul
Print_ISBN :
978-1-4673-5767-8
DOI :
10.1109/ASCC.2013.6606367
