Invivo drug delivery for cancer therapy using gold nanoparticle

Nanoparticle-based drug delivery provides many advantages, such as enhancing drug-therapeutic efficiency and pharmacological characteristics. Engineered gold nanoparticles have the potential to revolutionize the diagnosis and the therapy of several diseases, particularly by targeted delivery of anticancer drugs and imaging contrast agents. In this study, a nanodrug delivery system for anticancer is designed, characterized using TEM, SEM and FT-IR and used for invivo cancer therapy. Two groups of mice were taken and cancer was induced using two different chemical carcinogens and the incidence of tumor was confirmed by invasive and non-invasive methods. In one group of mice, liver cancer was induced by administering Sodium dichromate. On the other group of mice, there was no incidence of tumor after 4 weeks which were administered with 4-NQO and Arecoline. The nanodrug delivery system is used for treatment in cancer induced mice. The treated mice were monitored and improvements were observed in their physical activity. Further confirmation for tumor growth inhibition using nanodrug delivery system is still under progress.