Title :
Novel device to trend impedance and fluorescence of the cervix for preterm birth detection
Author :
Etemadi, Mozziyar ; Chung, Pau-Choo ; Heller, J. Alex ; Liu, Jiangchuan ; Grossman-Kahn, Rebecca ; Rand, Larry ; Roy, Sandip
Author_Institution :
Dept. of Bioeng. & Therapeutic Sci., Univ. of California, San Francisco, San Francisco, CA, USA
Abstract :
Preterm birth is the leading cause of worldwide neonatal mortality. It follows a pathologically accelerated form of the normal processes that govern cervical softening and dilation. Softening and dilation occur due to changes in cervical collagen crosslinking, which can be measured non-invasively by changes in tissue fluorescence and impedance. We present a novel device designed specifically to take fluorescence and impedance measurements throughout pregnancy, with the end goal of fusing and trending these measurements to form an early diagnosis of preterm labor.
Keywords :
biological tissues; biomedical equipment; biomedical measurement; electric impedance measurement; fluorescence; molecular biophysics; obstetrics; patient diagnosis; proteins; cervical collagen crosslinking; cervical dilation; cervical softening; fluorescence measurements; impedance measurements; neonatal mortality; patient diagnosis; pregnancy; preterm birth detection; preterm labor; tissue fluorescence; tissue impedance; Electrodes; Fluorescence; Impedance; Impedance measurement; Optical fiber devices; Pregnancy; Sea measurements;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6609466
