Novel device to trend impedance and fluorescence of the cervix for preterm birth detection

Author

Etemadi, Mozziyar ; Chung, Pau-Choo ; Heller, J. Alex ; Liu, Jiangchuan ; Grossman-Kahn, Rebecca ; Rand, Larry ; Roy, Sandip

Author_Institution

Dept. of Bioeng. & Therapeutic Sci., Univ. of California, San Francisco, San Francisco, CA, USA

fYear

2013

fDate

3-7 July 2013

Firstpage

176

Lastpage

179

Abstract

Preterm birth is the leading cause of worldwide neonatal mortality. It follows a pathologically accelerated form of the normal processes that govern cervical softening and dilation. Softening and dilation occur due to changes in cervical collagen crosslinking, which can be measured non-invasively by changes in tissue fluorescence and impedance. We present a novel device designed specifically to take fluorescence and impedance measurements throughout pregnancy, with the end goal of fusing and trending these measurements to form an early diagnosis of preterm labor.

Keywords

biological tissues; biomedical equipment; biomedical measurement; electric impedance measurement; fluorescence; molecular biophysics; obstetrics; patient diagnosis; proteins; cervical collagen crosslinking; cervical dilation; cervical softening; fluorescence measurements; impedance measurements; neonatal mortality; patient diagnosis; pregnancy; preterm birth detection; preterm labor; tissue fluorescence; tissue impedance; Electrodes; Fluorescence; Impedance; Impedance measurement; Optical fiber devices; Pregnancy; Sea measurements;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE

Conference_Location

Osaka

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2013.6609466

Filename

6609466