Title :
High-order sliding-mode control for anesthesia
Author :
Gallardo Hernandez, Ana ; Eslava Escobar, Jonathan ; Leder, Ron ; Hernandez Perez, Ana Luisa ; Fridman, L. ; Davila, Jorge ; Revilla Monsalve, Cristina ; Islas Andrade, Sergio
Author_Institution :
Centro Medico Nac. Siglo XXI (IMSS), Unidad de Investig. en Enfermedades Metabolicas del Hosp. de Cardiologia, México City, Mexico
Abstract :
Depth of anesthesia can be indirectly measured by Bispectral Index (BIS), therefore it is possible to administer propofol in a closed loop to maintain the optimal level of anesthesia while minimizing the dose to improve the postanesthesia recovery. High-Order Sliding-Mode control can be used to individualize drug dosing. In this study, the controller is tested with four in silico patients.
Keywords :
closed loop systems; drugs; medical control systems; variable structure systems; anesthesia; bispectral index; closed loop; drug dosing; high-order sliding-mode control; in silico patients; propofol; Anesthesia; Brain modeling; Drugs; Indexes; Robustness; Sliding mode control; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6609472
