Title :
High-resolution broadly-tunable MOPA-based terahertz spectrometer to non-destructively probe and modulate protein electrodynamics
Author :
Lewis, Richard J. ; Ee-Leong Lim ; Rowe, David J. ; Alam, Shaif-Ul ; Nilsson, Johan ; Chan-Wook Baik ; Gurel, Ogan ; Wilkinson, J.S. ; Richardson, D.J.
Author_Institution :
Optoelectron. Res. Centre, Univ. of Southampton, Southampton, UK
Abstract :
We report on the development of a high-resolution (<; 1 GHz at 1.0 THz), broadly-tunable (~0.5 - 3.0 THz) fiber MOPA-based terahertz spectrometer system. The flexibility and performance of this system will be demonstrated with gaseous (water vapor) and aqueous (water and solvated protein) samples with a view towards selectively and non-destructively probing functionally significant large-scale protein motions.
Keywords :
bioelectric phenomena; biological techniques; molecular biophysics; proteins; terahertz spectroscopy; high resolution broadly tunable MOPA based terahertz spectrometer; large scale protein motion; nondestructive probe; protein electrodynamics modulation; Atmospheric measurements; Biomedical optical imaging; Optical polarization; Optical pumping; Optical reflection; Particle measurements; Time-frequency analysis;
Conference_Titel :
Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2013 38th International Conference on
Conference_Location :
Mainz
DOI :
10.1109/IRMMW-THz.2013.6665817
