Title :
An implantable microsystem for long-term study on the mechanism of deep brain stimulation
Author :
Yu-Po Lin ; Hung-Chih Chiu ; Pin-Yang Huang ; Zong-Ye Wang ; Hsiang-Hui Cheng ; Po-Chiun Huang ; Kea-Tiong Tang ; Hsi-Pin Ma ; Hsin Chen
Author_Institution :
Dept. of Electr. Eng., Nat. Tsing Hua Univ., Hsinchu, Taiwan
fDate :
Oct. 31 2013-Nov. 2 2013
Abstract :
Deep brain stimulation (DBS) has been found useful for treating neural diseases such as the Parkinson´s disease, while the mechanism is not well understood and the DBS is suspected of inducing various side effects. This paper presents a microsystem suitable for studying the mechanism of the DBS. The microsystem contains eight channels of neural recording and stimulation circuits, an analog-to-digital converter, and a digital information hub. In addition, to facilitate long-term study, the microsystem is implantable and batteryless. Both power and data are transmitted wirelessly through a single coil by the time-division-multiple-access (TDMA) technique. The microsystem has been designed and fabricated with the 0.18μm CMOS technology. The pilot testing results are presented and discussed.
Keywords :
CMOS integrated circuits; analogue-digital conversion; bioMEMS; bioelectric potentials; biomedical electronics; brain; diseases; medical disorders; neurophysiology; prosthetics; CMOS technology; DBS; Parkinson´s disease; TDMA technique; analog-digital converter; deep brain stimulation mechanism; digital information hub; implantable microsystem; neural disease treatment; neural recording circuits; neural stimulation circuits; pilot testing; power data; side effects; single coil; time-division-multiple-access technique; Amplitude shift keying; Choppers (circuits); Coils; Current measurement; Data communication; Satellite broadcasting; Wireless communication;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2013 IEEE
Conference_Location :
Rotterdam
DOI :
10.1109/BioCAS.2013.6679692
