Characterization of a non linear fractional model of electrode-tissue impedance for neuronal stimulation

Author

Kolbl, F. ; Sabatier, J. ; N´Kaoua, Gilles ; Naudet, Frederic ; Faggiani, Emilie ; Benazzouz, Abdelhamid ; Renaud, S. ; Lewis, N.

Author_Institution

IMS, Univ. of Bordeaux, Talence, France

fYear

2013

fDate

Oct. 31 2013-Nov. 2 2013

Firstpage

338

Lastpage

341

Abstract

The design of neuro-stimulators must include a realistic model of electrode-tissue interface. Complex electrochemical phenomena associated to high levels of stimulation current give fractional and non linear behavior to this interface that simple linearized models fail to fit. This paper describes both a measurement protocol based on biphasic current-controlled solicitations and a modeling procedure relying on an original approach of multi-model, taking into account the non-linear and fractional effects. This model fits correctly the measurement results with current levels varying from 50μA to 1mA. Furthermore the whole characterization protocol can be safely transposed to in vivo measurements.

Keywords

bioelectric potentials; biological tissues; biomedical electrodes; electric immittance measurement; electrochemical electrodes; neurophysiology; physiological models; biphasic current-controlled solicitations; electrochemical phenomena; electrode-tissue impedance; electrode-tissue interface model; neuronal stimulation; nonlinear fractional model; stimulation current; Artificial neural networks; Biomedical measurement; Computational modeling; Electric variables measurement; Electrodes; Fractals; Generators;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2013 IEEE

Conference_Location

Rotterdam

Type

conf

DOI

10.1109/BioCAS.2013.6679708

Filename

6679708