Title :
Utilization of Default Logic for Analyzing a Metabolic System in Discrete Time
Author :
Tan Le ; Doncescu, Andrei ; Siegel, P.
Author_Institution :
Lab. for Anal. & Archit. of Syst., Univ. of Toulouse, Toulouse, France
Abstract :
Metabolic pathways are seen as high criticalities in our understanding of mechanisms of biological functions. This article focuses on automatic synthesis of the metabolic pathways from factors in the domain of discrete time. An essential component of this approach is using default logic to acquire facts about biological knowledge of intracellular communication. By choosing an adequate representation of biological knowledge, the "reasoning" is able to assign in acquisition of the facts and extract interactions necessary for the synthesis of the metabolic pathways or signaling.
Keywords :
biology computing; formal logic; inference mechanisms; knowledge representation; automatic metabolic pathways synthesis; biological functions; biological knowledge; biological knowledge representation; default logic utilization; discrete time; intracellular communication; metabolic pathways; metabolic system; reasoning; Biological system modeling; Equations; Mathematical model; Production; Proteins;
Conference_Titel :
Computational Science and Its Applications (ICCSA), 2013 13th International Conference on
Conference_Location :
Ho Chi Minh City
DOI :
10.1109/ICCSA.2013.27