Biochemical liquids permittivity characterization technique based on whispering-gallery mode resonator with microfluidic channel

Author

Gubin, Alexey I. ; Barannik, Alexander A. ; Protsenko, I.A. ; Cherpak, Nickolay T. ; Offenhaeusser, A. ; Vitusevich, S.

Author_Institution

Dept. of Solid State Radiophys., IRE NAS of Ukraine, Kharkiv, Ukraine

fYear

2013

fDate

6-10 Oct. 2013

Firstpage

314

Lastpage

317

Abstract

We present the accurate microwave characterization technique for measuring the complex permittivity of biochemical liquids of sub-microliter/nanoliter volumes. The technique is developed on the basis of high-quality whispering-gallery mode sapphire resonator with microfluidic channel filled with liquid under test. Experimental data are obtained in Ka-band for the aqueous solution of cytochrome C, which can be used in the field of biosensors. To find the complex permittivity of the solution the special calibration procedure with application of COMSOL Multiphysics commercial software was performed.

Keywords

biochemistry; biosensors; microfluidics; permittivity; whispering gallery modes; Ka-band; biochemical liquids; biosensors; complex permittivity; cytochrome C; liquid under test; microfluidic channel; microwave characterization; permittivity characterization; sapphire resonator; whispering-gallery mode resonator; Liquids; Microfluidics; Microwave theory and techniques; Permittivity; Permittivity measurement; Q-factor; Resonant frequency; bioliquids; complex permittivity; cytochrome C; micro- to nanoliter scale; microfluidic channel; millimeter waves; whispering-gallery mode resonator;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave Conference (EuMC), 2013 European

Conference_Location

Nuremberg

Type

conf

Filename

6686654