Biopsy analysis using a quadruple infrared sensor

Author

Fioravanti, Valeria ; Weber, E. ; van den Driesche, S. ; Vellekoop, Michael J. ; Pucciarelli, Daniela ; Breiteneder, Heimo ; Hafner, Christian

Author_Institution

Inst. for Microsensors, -Actuators & -Syst. (IMSAS/MCB), Univ. of Bremen, Bremen, Germany

fYear

2013

fDate

3-6 Nov. 2013

Firstpage

1

Lastpage

4

Abstract

In this contribution, infrared absorbance measurements by using a quadruple sensor have been performed for the first time to indicate the presence of cancer cells in melanoma biopsies. To verify the fidelity of the obtained results, they have been compared with results achieved by histopathology analysis and by using Fourier transform infrared (FTIR) spectroscopic imaging of tissue arrays. A significant agreement has been found between the different methods, demonstrating the potential of the quadruple infrared sensor as a label-free and cost-effective instrument to support the experts in their examination and diagnosis of tissue biopsies.

Keywords

Fourier transform spectroscopy; biological tissues; biomedical measurement; biomedical transducers; cancer; infrared detectors; infrared spectroscopy; FTIR; Fourier transform infrared spectroscopic imaging; cancer cell; histopathology analysis; infrared absorbance measurement; label-free cost-effective instrument; melanoma biopsy analysis; quadruple infrared sensor; tissue biopsy diagnosis; Biopsy; Cancer; Malignant tumors; Microscopy; Sensor systems; Skin;

fLanguage

English

Publisher

ieee

Conference_Titel

SENSORS, 2013 IEEE

Conference_Location

Baltimore, MD

ISSN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2013.6688476

Filename

6688476