Prescreening seizure-like events in a rat model of epilepsy A: A 2D video processing method

Author

Christ, O. ; Somerlik-Fuchs, Karin H. ; Stieglitz, T. ; Schulze-Bonhage, A. ; Hofmann, U.G.

Author_Institution

Dept. of Neurosurg., Res. Group for Neuroelectron. Syst., Univ. Hosp. Freiburg, Freiburg, Germany

fYear

2013

fDate

6-8 Nov. 2013

Firstpage

113

Lastpage

116

Abstract

Temporal lobe epilepsy is the most common cause of drug-resistant seizures. Electrical stimulation seems to be a promising alternative to the classical anteromesial temporal resection. Our work aims at improving and validating therapeutic approaches for treating temporal lobe epilepsy using high-frequency stimulation. The relative phase clustering index (rPCI) is used to describe the epileptogenicity of a brain region and seizure prediction. A 2D image processing algorithm is presented for facilitating the tedious and time consuming visual image inspection of long term video footage required to determine optimal electrical stimulation parameters. See our companion paper describing the 3D solution in this journal.

Keywords

brain; diseases; medical image processing; neuromuscular stimulation; patient rehabilitation; video signal processing; 2D image processing algorithm; 2D video processing; anteromesial temporal resection; brain region; drug-resistant seizure; electrical stimulation; epileptogenicity; high-frequency stimulation; prescreening seizure-like event; rPCI; rat model; relative phase clustering index; seizure prediction; temporal lobe epilepsy; therapeutic approach; visual image inspection; Algorithm design and analysis; Brain modeling; Epilepsy; Histograms; Surgery; Temporal lobe; Time series analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on

Conference_Location

San Diego, CA

ISSN

1948-3546

Type

conf

DOI

10.1109/NER.2013.6695884

Filename

6695884