Implantable neural device integrated with regenerative scaffold for neural signal sensing from damaged spinal cord

A novel neural device that is a combination of the hydrogel scaffold for regeneration and neural electrode for signal acquisition methods is suggested and fabricated to sense the signal from the damaged spinal cord. The sieve-type electrodes have been designed into a semicircle shape to be fit to a hemisection lesion model of an in-vivo implant animal model. A total of six ring-shaped electrodes are arrayed with a pitch of 600μιη and via holes with a diameter of 200μιη. Exactly overlapping the ring electrode with the neural electrode to the channels of axonal regeneration in the nerve regeneration scaffold is the most important task during the integration process of the scaffold and sieve electrode. The neural electrode was fabricated on polyimide of 30μιη thickness, and has 6 circular sieve electrodes, which have an average impedance of 17.9kΩ at 1kHz.