Title :
Modeling of abdominal aortic aneurism rupture by using experimental bubble inflation test
Author :
Koncar, Igor ; Nikolic, D. ; Pantovic, Suzana ; Rosic, Marko ; Mijailovic, Nikola ; Ilic, Nemanja ; Dragas, Marko ; Maksimovic, Zivan ; Davidovic, Lazar ; Filipovic, Nenad D.
Author_Institution :
Clinic for Vascular & Endovascular Surg., Univ. of Belgrade, Belgrade, Serbia
Abstract :
Aneurysm rupture is a biomechanical phenomenon that occurs when the mechanical stress acting on the inner wall exceeds the failure strength of the diseased aortic tissue. Besides numerous advantages in surgical and anaesthesiological management, emergency procedure leads to fatal outcome in 20-50% of those who reach hospital. Prediction of influence of dynamic blood flow on natural history of aneurysmatic disease and outcome of therapeutic procedures could contribute to treatment strategy and results. In this study we presented experimental design for estimation of the material property of real human aorta tissue from bubble inflation test. Then we investigated fluid-structure interaction of pulsatile blood flow in the specific patient three-dimensional model of abdominal aortic aneurysms (AAAs). Numerical predictions of blood flow patterns and nonlinear wall stresses in AAAs are performed in compliant wall anisotropic model using the finite element method. These computational procedures together with experimental determination of the nonlinear material property could provide us more accurate assessment of aneurysm rupture risk.
Keywords :
biomechanics; diseases; finite element analysis; haemodynamics; pulsatile flow; surgery; abdominal aortic aneurism rupture; anaesthesiological management; aneurysmatic disease; biomechanical phenomenon; blood flow patterns; bubble inflation test; compliant wall anisotropic model; diseased aortic tissue; dynamic blood flow; failure strength; finite element method; fluid-structure interaction; hospital; mechanical stress; nonlinear material property; nonlinear wall stresses; numerical predictions; patient treatment strategy; pulsatile blood flow; real human aorta tissue; specific patient three-dimensional model; surgical management; therapeutic procedures; Aneurysm; Blood flow; Computational modeling; Fluids; Solid modeling; Stress; Surgery;
Conference_Titel :
Bioinformatics and Bioengineering (BIBE), 2013 IEEE 13th International Conference on
Conference_Location :
Chania
DOI :
10.1109/BIBE.2013.6701612