Application of genetically engineered Salmonella typhimurium as tumor targeting agents

Author

Yeongjin Hong ; Seung-Hwan Park ; Seong Young Kwon ; Jung-Joon Min

Author_Institution

Med. Sch., Dept. of Microbiol., Chonnam Nat. Univ., Gwangju, South Korea

fYear

2013

fDate

20-23 Oct. 2013

Firstpage

1504

Lastpage

1507

Abstract

Some attenuated bacteria have been studied as viable tumor-targeting agents. Among them, Salmonella typhimurium carrying many advantages such as growth in both of aerobic and anaerobic conditions, various attenuated virulent strains, universal genetic engineering tools, and the clarified full genome sequences has been studied the most up to now. In this paper, we review recent progresses of tumor treatment using this bacterium.

Keywords

cancer; cellular biophysics; gene therapy; genetic engineering; genomics; microorganisms; tumours; anaerobic condition; attenuated bacteria; attenuated virulent strains; bacteria growth; full genome sequences; genetically engineered Salmonella typhimurium; tumor targeting agents; tumor treatment; universal genetic engineering tools; viable tumor-targeting agent; Abstracts; Bioinformatics; Genomics; Immune system; Materials; Tumors; Vectors; Salmonella; delivery; diagnosis; targeting; therapy; tumor;

fLanguage

English

Publisher

ieee

Conference_Titel

Control, Automation and Systems (ICCAS), 2013 13th International Conference on

Conference_Location

Gwangju

ISSN

2093-7121

Print_ISBN

978-89-93215-05-2

Type

conf

DOI

10.1109/ICCAS.2013.6704125

Filename

6704125