Title :
Application of genetically engineered Salmonella typhimurium as tumor targeting agents
Author :
Yeongjin Hong ; Seung-Hwan Park ; Seong Young Kwon ; Jung-Joon Min
Author_Institution :
Med. Sch., Dept. of Microbiol., Chonnam Nat. Univ., Gwangju, South Korea
Abstract :
Some attenuated bacteria have been studied as viable tumor-targeting agents. Among them, Salmonella typhimurium carrying many advantages such as growth in both of aerobic and anaerobic conditions, various attenuated virulent strains, universal genetic engineering tools, and the clarified full genome sequences has been studied the most up to now. In this paper, we review recent progresses of tumor treatment using this bacterium.
Keywords :
cancer; cellular biophysics; gene therapy; genetic engineering; genomics; microorganisms; tumours; anaerobic condition; attenuated bacteria; attenuated virulent strains; bacteria growth; full genome sequences; genetically engineered Salmonella typhimurium; tumor targeting agents; tumor treatment; universal genetic engineering tools; viable tumor-targeting agent; Abstracts; Bioinformatics; Genomics; Immune system; Materials; Tumors; Vectors; Salmonella; delivery; diagnosis; targeting; therapy; tumor;
Conference_Titel :
Control, Automation and Systems (ICCAS), 2013 13th International Conference on
Conference_Location :
Gwangju
Print_ISBN :
978-89-93215-05-2
DOI :
10.1109/ICCAS.2013.6704125
