Title :
Use of bacterial cellulose-glycerol-poly(vinyl alcohol) composites in drug release
Author :
Pavaloiu, Ramona-Daniela ; Dobre, Tanase ; Hlevca, Cristina
Author_Institution :
Fac. of Appl. Chem. & Mater. Sci., Univ. Politeh. of Bucharest, Bucharest, Romania
Abstract :
Bacterial cellulose (BC) is a biomaterial suited for various biomedical applications, due to its unique nanostructure, that confers remarkable physical and chemical properties, such as: excellent elasticity, biocompatibility, high purity, high tensile strength and high elastic modulus. The article describes the mechanism and amoxicillin release profiles from bacterial cellulose-glycerol-poly(vinyl alcohol) composites, in the aim to use such systems in controlled drug delivery field. Obtained data from these composites were slightly smaller than BC-Glycerol, probably due to the fact that PVA layers provide an additional barrier for drug release. The presented data are of interest for the biomaterials community.
Keywords :
biomedical materials; drug delivery systems; drugs; elastic moduli; elasticity; microorganisms; nanocomposites; nanofabrication; nanomedicine; polymers; tensile strength; amoxicillin release profiles; bacterial cellulose-glycerol-poly(vinyl alcohol) composites; biocompatibility; biomaterial; biomedical applications; chemical properties; controlled drug delivery field; drug release; elastic modulus; elasticity; nanostructure; physical properties; purity; tensile strength; Biomembranes; Communities; Correlation; Drugs; Mechanical factors; Quantum cascade lasers; bacterial cellulose; biomaterial; drug release;
Conference_Titel :
E-Health and Bioengineering Conference (EHB), 2013
Conference_Location :
Iasi
Print_ISBN :
978-1-4799-2372-4
DOI :
10.1109/EHB.2013.6707312
