Title :
Local environmental control by world-to-chip interface microchip and pipette
Author :
Nogawa, Kousuke ; Arai, Fumihito
Author_Institution :
Inst. for Adv. Res., Nagoya Univ., Nagoya, Japan
Abstract :
Bio-actuated, especially flagellated bacteria-driven, microrobots have been actively studied to develop novel technologies such as microsurgery inside human body, though the characteristics of the bacterial flagellar motor have not been sufficiently investigated. For analysis of the flagellar motor, we previously proposed the local environmental control system with nano/micro dual pipettes to change local ion/reagent concentration arbitrarily. However, in this system, over time, the local ion/reagent could not be fully flushed out due to the increase of the diffusion rate caused by high ion/reagent concentration in the bath. So, in this paper, to achieve more arbitrary local environmental control, we propose the local environmental control by world-to-chip interface microchip (WtCI) and pipette. We develop the system and demonstrate the feasibility of the local environmental control by WtCI microchip and pipette.
Keywords :
bioMEMS; biodiffusion; cellular transport; medical robotics; microfluidics; microorganisms; microrobots; surgery; WtCI microchip; WtCI pipette; arbitrary local environmental control; bacteria-driven microrobots; bacterial flagellar motor; bio-actuation; diffusion rate; high-ion-reagent concentration; human body; microsurgery; world-to-chip interface microchip; world-to-chip interface pipette; Biomedical optical imaging; Educational institutions; Microfluidics; Microorganisms; Optical device fabrication; Optical mixing;
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2013 International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4799-1527-9
DOI :
10.1109/MHS.2013.6710421