Construction of artificial motile cell model

Cytoskeletal system, which consists of actin, microtubule (MT), and their collaborating proteins and molecular motors, is a native superior micro machine. In order to utilize the performance, attempts to generate various molecular motions in vitro using purified actin, myosin, and their associating proteins, and studies to develop cell-sized liposomes incorporating active actomyosin inside have been performed. Here, we introduce some of the outcomes, and describe problems to be overcome and outlook for the future.