On-chip enucleation of oocyte using untetherd micro-robot with gripping mechanism

Author

Ichikawa, Akihiko ; Sakuma, Shinya ; Shoda, Takuya ; Arai, Fumihito ; Akagi, S.

Author_Institution

Dept. of Mechatron. Eng., Meijo Univ., Nagoya, Japan

fYear

2013

fDate

10-13 Nov. 2013

Firstpage

1

Lastpage

3

Abstract

We developed a highly functional untethered micro-robot that can manipulate cells with high gripping force in a micro-fluidic chip. The robot has gripping mechanism which is actuated by magnetic power. A permanent magnet is attached at the center of the gripping mechanism, and an electrical magnet controls the position of the magnet from the bottom of the micro-fluidic chip. The open-close accuracy of the gripper is about 3.0 μm. We succeeded in cutting of zona pelucida of oocyte and enucleation by using this micro-robot.

Keywords

bioMEMS; cellular biophysics; medical robotics; microfluidics; microrobots; permanent magnets; electrical magnet controls; functional untethered microrobot; gripping mechanism; high-gripping force; magnetic power; manipulate cells; microfluidic chip; on-chip enucleation; oocyte; open-close accuracy; permanent magnet; zona pelucida; Accuracy; Cloning; Fabrication; Magnetic hysteresis; Permanent magnets; Robots; Silicon;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro-NanoMechatronics and Human Science (MHS), 2013 International Symposium on

Conference_Location

Nagoya

Print_ISBN

978-1-4799-1527-9

Type

conf

DOI

10.1109/MHS.2013.6710479

Filename

6710479