DocumentCode :
674491
Title :
Non-linear dynamic analysis of RR signals in patients with and without excessive daytime sleepiness
Author :
Melia, Umberto ; Guaita, Marc ; Vallverdu, Montserrat ; Claria, Francisco ; Caminal, Pere ; Embid, Cristina ; Vilaseca, Isabel ; Salamero, Manel ; Santamaria, J.
Author_Institution :
Dept. ESAII, Univ. Politec. de Catalunya, Barcelona, Spain
fYear :
2013
fDate :
22-25 Sept. 2013
Firstpage :
449
Lastpage :
452
Abstract :
Linear and non-linear measures applied to heart rate variability (HRV) can be used to quantify modulation of the sympathetic and parasympathetic branches of the autonomic nervous system. RR signals were obtained from the ECG recorded during five Maintenance of Wakefulness (MWT) and Multiple Sleep Latency (MSLT) tests alternated throughout the day from patients suffering sleep disturbance. Two different end-points were considered: Study A, excessive daytime sleepiness (EDS) versus without daytime sleepiness (WDS); Study B, Pre-CPAP versus Post-CPAP (continuous positive airway pressure therapy) in EDS. Measures obtained from spectral analysis (PSD), time-frequency representation (TFR), auto-correntropy (ACORR) and auto-mutual-information function (AMIF) were applied to describe autonomic nervous system activity and RR regularity. Statistical differences between EDS and WDS groups were found in MSLT events. During MSLT, the parasympathetic activity and RR regularity in EDS were affected by CPAP therapy. Non-linear measures obtained from EDS in Post-CPAP differed from Pre-CPAP (p-value<;0.05) and tended to be similar to WDS.
Keywords :
cardiovascular system; electrocardiography; entropy; medical disorders; medical signal processing; neurophysiology; nonlinear dynamical systems; patient treatment; pneumodynamics; signal representation; sleep; spectral analysis; statistical analysis; time-frequency analysis; ACORR; AMIF; CPAP therapy; ECG; EDS groups; HRV; MSLT events; MWT; Maintenance of Wakefulness tests; Multiple Sleep Latency tests; PSD; RR regularity; RR signal; TFR; WDS groups; auto-correntropy; auto-mutual-information function; autonomic nervous system activity; continuous positive airway pressure therapy; end-points; excessive daytime sleepiness; heart rate variability; nonlinear dynamic analysis; nonlinear measures; parasympathetic activity; parasympathetic branch modulation; post-CPAP; pre-CPAP; sleep disturbance; spectral analysis; statistical differences; time-frequency representation; without daytime sleepiness; Abstracts; Entropy; Sleep;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computing in Cardiology Conference (CinC), 2013
Conference_Location :
Zaragoza
ISSN :
2325-8861
Print_ISBN :
978-1-4799-0884-4
Type :
conf
Filename :
6713410
Link To Document :
بازگشت