Title :
Extending the visualization capabilities of a genome browser
Author :
Lamfalusi, Csaba ; Girus, David ; Kruppa, Kinga ; Toth, Janos ; Pocsai, Eniko Hajdune ; Kunkli, Roland ; Hajdu, Andras ; Balint, Balint L.
Author_Institution :
Fac. of Inf., Univ. of Debrecen, Debrecen, Hungary
Abstract :
Scalable visualization of big data is highly desired in several fields. A demonstrative example is annotated genetic data, where the DNA sequence can be better visualized using space-filling fractal curves. Though such approaches are already available in the literature, they are not applied routinely in the clinical practice. The reason of this undesired fact is that clinicians use well-established, but rather old gene browsers in their work. Naturally, these browsers lack state-of-the-art programming support and also visualization features. To help with this problem, in this paper, we propose a completion of a very widely used genome browser with scalable visualization techniques. The motivation of the work came from the clinical partner, since a good overview of the whole annotated DNA segment can lead to the recognition of currently unknown relations between genes. We explain what steps were needed to add the new visualization feature to the browser in terms of graphical elements, data extraction, and a scalable user interface.
Keywords :
biology computing; data visualisation; genetic algorithms; user interfaces; DNA segment; DNA sequence; data extraction; genetic data; genome browser; graphical elements; old gene browsers; scalable user interface; scalable visualization techniques; space filling fractal curves; visualization capabilities; Bioinformatics; Browsers; DNA; Data visualization; Genomics; Java; Customizable content management; Genome browsing; Information visualization; Scalable data analytics; Space-filling curves;
Conference_Titel :
Cognitive Infocommunications (CogInfoCom), 2013 IEEE 4th International Conference on
Conference_Location :
Budapest
Print_ISBN :
978-1-4799-1543-9
DOI :
10.1109/CogInfoCom.2013.6719283