Element identification in organic samples utilizing a benchtop X-ray fluorescence emission tomography (XFET) system

Author

Groll, A. ; George, Jinto ; La Riviere, P.J. ; Meng, L.J.

Author_Institution

Nucl., Plasma, & Radiol. Eng., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA

fYear

2013

fDate

Oct. 27 2013-Nov. 2 2013

Firstpage

1

Lastpage

6

Abstract

Synchrotron-based X-ray fluorescence computed tomography (XFCT) is a common technique for mapping metal ions in biological specimens. In recent years, it has been demonstrated that various metal ions could play critical roles in disease and general biological functions. In this work, we are developing a benchtop x-ray fluorescence emission tomography system that utilizes combines charge-coupled device (CCD) detectors and special emission tomography apertures to obtain 3-D mapping of elemental distribution in intact biological samples. We have carried out a series of studies that utilize multiple slit apertures and a monochromatic pencil beam x-ray source to image a triple-tube sample and an osmium stained zebrafish.

Keywords

CCD image sensors; X-ray imaging; X-ray monochromators; X-ray tubes; emission tomography; fluorescence; 3D elemental distribution mapping; CCD detector; XFCT; XFET system; benchtop X-ray fluorescence emission tomography system; biological specimen function; charge-coupled device detector; element identification; metal ion mapping technique; monochromatic pencil beam X-ray source; organic sample; osmium stained zebrafish; special emission tomography aperture; synchrotron-based X-ray fluorescence computed tomography; triple-tube sample; Apertures; Detectors; Fluorescence; Imaging; Photonics; Scattering; X-ray imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2013 IEEE

Conference_Location

Seoul

Print_ISBN

978-1-4799-0533-1

Type

conf

DOI

10.1109/NSSMIC.2013.6829026

Filename

6829026