Title :
Element identification in organic samples utilizing a benchtop X-ray fluorescence emission tomography (XFET) system
Author :
Groll, A. ; George, Jinto ; La Riviere, P.J. ; Meng, L.J.
Author_Institution :
Nucl., Plasma, & Radiol. Eng., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA
fDate :
Oct. 27 2013-Nov. 2 2013
Abstract :
Synchrotron-based X-ray fluorescence computed tomography (XFCT) is a common technique for mapping metal ions in biological specimens. In recent years, it has been demonstrated that various metal ions could play critical roles in disease and general biological functions. In this work, we are developing a benchtop x-ray fluorescence emission tomography system that utilizes combines charge-coupled device (CCD) detectors and special emission tomography apertures to obtain 3-D mapping of elemental distribution in intact biological samples. We have carried out a series of studies that utilize multiple slit apertures and a monochromatic pencil beam x-ray source to image a triple-tube sample and an osmium stained zebrafish.
Keywords :
CCD image sensors; X-ray imaging; X-ray monochromators; X-ray tubes; emission tomography; fluorescence; 3D elemental distribution mapping; CCD detector; XFCT; XFET system; benchtop X-ray fluorescence emission tomography system; biological specimen function; charge-coupled device detector; element identification; metal ion mapping technique; monochromatic pencil beam X-ray source; organic sample; osmium stained zebrafish; special emission tomography aperture; synchrotron-based X-ray fluorescence computed tomography; triple-tube sample; Apertures; Detectors; Fluorescence; Imaging; Photonics; Scattering; X-ray imaging;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2013 IEEE
Conference_Location :
Seoul
Print_ISBN :
978-1-4799-0533-1
DOI :
10.1109/NSSMIC.2013.6829026
