A feasibility study of portable compton camera for metastatic lymph node detection

Author

Nakamura, Yoshihiko ; Shimazoe, Kenji ; Iriya, T. ; Okumura, Yukihiko ; Takahashi, Masaharu ; Matsusaka, Kento ; Fukayama, M. ; Momose, T. ; Seto, Yoshihiro ; Takahashi, Hiroki

Author_Institution

Dept. of Bioeng., Univ. of Tokyo, Tokyo, Japan

fYear

2013

fDate

Oct. 27 2013-Nov. 2 2013

Firstpage

1

Lastpage

3

Abstract

We are developing a portable Compton camera to be placed inside the human body for local inspection of metabolic functions of metastatic lymph node in gastric cancer. Before fabricating the portable Compton camera, Radioactivity measurement of metastatic and non-metastatic lymph nodes with an injection of FDG was conducted at the University of Tokyo Hospital. The detector that used to measure the radioactivity is composed of a 5mm × 5mm × 5mm GAGG scintillation crystal [2], a Hamamatsu Si-APD, an ASIC and a FPGA and size of the read-out board is 13 × 80 mm. The maximum radioactivity of FDG was about 7kBq. A Monte Carlo simulation result of the portable Compton camera shows that 7kBq phantoms can be imaged within 2 minutes.

Keywords

Compton effect; Monte Carlo methods; application specific integrated circuits; avalanche photodiodes; biochemistry; biological organs; biomedical electronics; biomedical equipment; cameras; cancer; field programmable gate arrays; phantoms; portable instruments; radioactivity measurement; radioisotope imaging; readout electronics; scintillation; silicon radiation detectors; ASIC; FPGA; GAGG scintillation crystal; Hamamatsu Si-APD; Monte Carlo simulation; Si; feasibility study; gastric cancer; human metastatic lymph node; local metabolic function inspection; maximum FDG radioactivity; metastatic lymph node detection; nonmetastatic lymph node; phantom imaging; portable Compton camera development; portable Compton camera fabrication; radioactivity 7 kBq; radioactivity detector; radioactivity measurement; read-out board size; size 13 mm; size 5 mm; size 80 mm; time 2 min; Cameras; Cancer; Detectors; Educational institutions; Image reconstruction; Lymph nodes; Phantoms; Compton camera; Intraoperative diagnosis; acceleration;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2013 IEEE

Conference_Location

Seoul

Print_ISBN

978-1-4799-0533-1

Type

conf

DOI

10.1109/NSSMIC.2013.6829334

Filename

6829334