Title :
Diagnosis of hepatic fibrosis using a multiphoton nonlinear optical microspectroscopy imaging system
Author :
Jang Hyuk Lee ; Jong Chul Kim ; Giyoong Tae ; Myoung-Kyu Oh ; Do-Kyeong Ko
Author_Institution :
Dept. of Phys. & Photon Sci., Gwangju Inst. of Sci. & Technol., Gwangju, South Korea
Abstract :
A photonic crystal fiber (PCF)-based multimodal multiphoton nonlinear microspectroscopy imaging system was developed and applied to hepatic fibrosis tissue. Multiphoton images and CARS spectrum at C-H vibration stretching differentiate liver fibrosis from normal liver tissue.
Keywords :
biomedical optical imaging; coherent antiStokes Raman scattering; diseases; holey fibres; liver; multiphoton processes; nonlinear optics; photonic crystals; C-H vibration stretching; CARS spectrum; PCF-based multimodal multiphoton nonlinear microspectroscopy imaging system; hepatic fibrosis tissue diagnosis; liver fibrosis tissue diagnosis; photonic crystal fiber; Fiber nonlinear optics; Liver; Optical fiber sensors; Optical fibers; Optical imaging;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2013 Conference on
Conference_Location :
San Jose, CA
