DocumentCode :
688625
Title :
Red-emitting substrates for rapid botulinum neurotoxin detection
Author :
Herron, James N. ; Engelhardt, Konrad H. ; O´Mel, Vlad
Author_Institution :
Dept. of Pharm. & Pharm. Chem., Univ. of Utah, Salt Lake City, UT, USA
fYear :
2013
fDate :
9-14 June 2013
Firstpage :
1
Lastpage :
2
Abstract :
We report a new red-emitting molecular beacon for botulinum neurotoxin A suitable inexpensive rapid assay formats. Reaction kinetics including parameters like Km and Vmax were evaluated in a fluorogenic assay using the BoNT/A light chain.
Keywords :
biochemistry; biosensors; enzymes; fluorescence; molecular biophysics; molecular configurations; optical sensors; reaction kinetics; sensor arrays; toxicology; BoNT/A light chain; botulinum neurotoxin A; fluorogenic assay; inexpensive rapid assay formats; rapid botulinum neurotoxin detection; reaction kinetics; red-emitting molecular beacon; red-emitting substrates; Biomedical optical imaging; Fluorescence; Kinetic theory; Optical sensors; Proteins; Substrates;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2013 Conference on
Conference_Location :
San Jose, CA
Type :
conf
Filename :
6833000
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=688625
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