Title :
Imaging the noncentrosymmetric structural organization of tissues with interferometric Second Harmonic Generation microscopy
Author :
Rivard, Maxime ; Popov, Konstantin ; Laliberte, Mathieu ; Bertrand-Grenier, Antony ; Martin, F. ; Pepin, Henri ; Pfeffer, Christian P. ; Brown, C. ; Rammuno, Lora ; Legare, Francois
Author_Institution :
Centre Energie Mater. Telecommun., Inst. Nat. de la Rech. Sci., Varennes, QC, Canada
Abstract :
We image the relative orientation of organized groups of noncentrosymmetric molecules (like collagen or myosin) at the micron scale in biological tissues by combining interferometry and Second Harmonic Generation (SHG) microscopy.
Keywords :
biological tissues; biomedical optical imaging; light interferometry; molecular biophysics; optical harmonic generation; optical microscopy; proteins; SHG; biological tissues; collagen; interferometric second harmonic generation microscopy; myosin; noncentrosymmetric molecules; noncentrosymmetric structural organization imaging; relative orientation organized group image; Crystals; Frequency conversion; Interference; Microscopy; Muscles; Proteins; Tendons;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2013 Conference on
Conference_Location :
San Jose, CA
