Automated phase segmentation in cerebrospinal fluid infusion test

The disturbance in cerebrospinal fluid (CSF) circulation is believed to be one of the main causes of hydrocephalus and its variants. Resistance to CSF outflow (Rout) is a parameter, which indicates the degree of CSF disturbance. I is used as supplementary parameter in diagnosing NPH and is calculated by CSF infusion test. During the infusion test, the gradual increase in CSF pressure can be observed. This continuous CSF pressure signal is divided into three phases (i.e. baseline, transient and plateau phases). Rout is calculated by the difference between mean CSF pressure at baseline and plateau phases, divided by the CSF infusion rate. However, currently these phases are designated manually. To minimize inter- or intra operator variability, we suggest automated method which classifies ICP to three sections.