Title :
Quantitative modelling of growth and metabolism of CHO-K1 cell cultures in a serum free medium
Author :
Nasution, U. ; Verhoeye, F. ; Bastin, G. ; Agathos, S. ; Schneider, Y.-J.
Author_Institution :
CESAME, Univ. Catholique de Louvain, Louvain La Neuve, Belgium
Abstract :
A quantitative model of growth and metabolism of CH0-K1 cell culture in a serum-free medium is presented. The model is validated using five batch experiments with varying glucose and glutamine initial concentrations.
Keywords :
biotechnology; cellular biophysics; process control; sugar; CHO-K1 cell culture growth; CHO-K1 cell culture metabolism; Chinese hamster ovary; bioprocess modelling; glucose initial concentration; glutamine initial concentration; quantitative modelling; serum free medium; Amino acids; Equations; Estimation; Mathematical model; Proteins; Sugar; bioprocess modelling; kinetic parameter; metabolism;
Conference_Titel :
Control Conference (ECC), 2001 European
Conference_Location :
Porto
Print_ISBN :
978-3-9524173-6-2
