Title :
Human granulopoiesis — A new time delay model
Author :
Lehn, F. ; Tibken, B. ; Hofer, E.P.
Author_Institution :
Dept. of Meas., Univ. of Ulm, Ulm, Germany
fDate :
Aug. 31 1999-Sept. 3 1999
Abstract :
In this paper the modeling of the human granulopoiesis is investigated. This modeling is an important part of the further development of a decision support system to assist medical doctors in the treatment of irradiation injuries. Referring to an existing model of Fliedner and Steinbach we derive a new nonlinear time delay model of the human granulopoiesis with state dependent delays. Simulations showing the excellent agreement between our new model and the Fliedner-Steinbach model conclude the paper.
Keywords :
blood; cellular biophysics; delays; injuries; patient treatment; Fliedner-Steinbach model; decision support system; human granulopoiesis; irradiation injury treatment; nonlinear time delay model; state dependent delay; Analytical models; Belts; Biological system modeling; Delay effects; Delays; Mathematical model; Simulation; Biomathematical Modeling; Human Granulopoiesis; State Dependent Time Delays;
Conference_Titel :
Control Conference (ECC), 1999 European
Conference_Location :
Karlsruhe
Print_ISBN :
978-3-9524173-5-5
