Analyzing superparamagnetic iron oxide nanoparticles (spions) using electrical impedance spectroscopy

Conventional methods to evaluate the size of superparamagnetic iron oxide nanoparticles (SPIONs) and their coatings used in magnetic particle imaging (MPI) include photon cross-correlation spectroscopy (PCCS) [1], atomic force microscopy (AFM) [1] and transmission electron microscopy (TEM) [2]. There is however still a potential for improvement as they are expensive and only able to analyze small sample quantities. In this work, a new method using electrical impedance spectroscopy is evaluated. With this method, it is possible to analyze macroscopic samples at low costs.