Design and development of two component hydrogel ejector

Author

Dunkle, Thomas ; Deschamps, Jessica ; Dam, Connie ; Nair, Lakshmi S. ; Phil, M.

Author_Institution

Biomed. Eng. Program, Univ. of Connecticut, Storrs, CT, USA

fYear

2015

fDate

17-19 April 2015

Firstpage

1

Lastpage

2

Abstract

The purpose of this project is to design and develop a novel device which is capable of quickly extruding and injecting hydrogels, preferably capable of live cell entrapment, from the input of two solutions-one containing horseradish peroxidase and a modified chitosan, the other with hydrogen peroxide and modified chitosan. Several designs were drafted in Sketch Up, 3D printed, and tested to assess the degree of homogeneity of the ejected hydrogel film.

Keywords

biomedical equipment; cellular biophysics; drug delivery systems; enzymes; hydrogels; molecular biophysics; polymer films; three-dimensional printing; tissue engineering; wounds; 3D printing; SketchUp; degree-of-homogeneity; ejected hydrogel film; extruding hydrogels; horseradish peroxidase; hydrogen peroxide; live cell entrapment; modified chitosan; two-component hydrogel ejector; Drug delivery; Films; Hydrogen; Polymers; Three-dimensional displays; Tissue engineering; Wounds; drug delivery; horseradish peroxidase; hydrogel; hydrogel ejector; hydrogen peroxide; tissue engineering; wound healing;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast

Conference_Location

Troy, NY

Print_ISBN

978-1-4799-8358-2

Type

conf

DOI

10.1109/NEBEC.2015.7117089

Filename

7117089