Title :
Microelectrod fabrication for diagnosis and treatment of brain disorders
Author :
Acar, Merve ; Shamsi, Hamed ; Oyar, Oguzhan ; Ozbek, I. Yucel ; Hacimuftuoglu, Ahmet ; Cavusoglu, Bulent ; Oral, E. Argun ; Karacali, Tevhit ; Sonmez, Erdal ; Ertugrul, Mehmet ; Efeoglu, Hasan
Author_Institution :
Elektrik ve Elektron. Muhendisligi, ATATURK Univ., Erzurum, Turkey
Abstract :
In this study, it is aimed to produce microelectrodes which can be used in the detection of neurotransmitters that are related with brain disorders such as Parkinson, Epilepsy, and Schizophrenia and that exist in the central nervous system (CNS). A 4-channel, ceramic-based fabrication is performed towards this goal by using photolithographic methods. The time-current graphic response against the addition of H2O2 the produced microelectrode is analyzed in the calibration test. It is observed that the response is in stepwise form. In addition, limit of detection (LOD) of the produced microelectrodes and linearity values are shown to be within the desired ranges.
Keywords :
brain; calibration; ceramics; microelectrodes; neurophysiology; patient diagnosis; patient treatment; photolithography; 4-channel ceramic-based fabrication; Parkinson; brain disorder diagnosis; brain disorder treatment; calibration test; central nervous system; epilepsy; microelectrode fabrication; neurotransmitters detection; photolithographic methods; schizophrenia; time-current graphic response; Biomedical measurement; Fabrication; Films; In vivo; Metals; Microelectrodes; Neurotransmitters; biosensor; fabrication; microelectrode; voltametry;
Conference_Titel :
Signal Processing and Communications Applications Conference (SIU), 2015 23th
Conference_Location :
Malatya
DOI :
10.1109/SIU.2015.7130273
