In-vivo characterization of a 0.8 – 3 µVRMS input-noise versatile CMOS pre-amplifier

Author

Cota, Oscar F. ; Plachta, Dennis ; Stieglitz, Thomas ; Manoli, Yiannos ; Kuhl, Matthias

Author_Institution

Lab. for Biomed. Microtechnol. at the Dept. of Microsyst. Eng. (IMTEK, Univ. of Freiburg, Freiburg, Germany

fYear

2015

fDate

22-24 April 2015

Firstpage

458

Lastpage

461

Abstract

The following work presents a CMOS-integrated low-noise pre-amplifier (LNA) for bio-potential recordings, which is part of a multi-channel neural recording system. The versatile pre-amplifier channel features a tunable lower cut-off frequency from 0.2 Hz to 10 kHz, an upper cut-off frequency from 37.9 Hz to 11 kHz, and a middle-band gain from 41 to 45 dB. With its variable power consumption from 3.3 μW to 1 mW, the input-referred noise can be set from 2 down to 0.8 μV_RMS. The pre-amplifier, fabricated in a 0.35 μm CMOS process, was successfully tested for ECG, EMG, and EEG applications.

Keywords

CMOS integrated circuits; biomedical electronics; biomedical equipment; electrocardiography; electroencephalography; electromyography; low noise amplifiers; medical signal processing; neurophysiology; CMOS-integrated low-noise pre-amplifier; ECG applications; EEG applications; EMG applications; bio-potential recordings; cut-off frequency; in-vivo characterization; input-noise versatile CMOS pre-amplifier; input-referred noise; middle-band gain; multichannel neural recording system; power consumption; size 0.35 mum; Conferences; Neural engineering;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering (NER), 2015 7th International IEEE/EMBS Conference on

Conference_Location

Montpellier

Type

conf

DOI

10.1109/NER.2015.7146658

Filename

7146658