Broadband dielectric characterization of CHO-K1 cells using miniaturized transmission-line sensor

Author

Meyne, Nora ; Fuge, Grischa ; Hemanth, Suhith ; Trieu, Hoc Khiem ; An-Ping Zeng ; Jacob, Arne F.

Author_Institution

Inst. fur Hochfrequenztech., Tech. Univ. Hamburg-Harburg, Hamburg, Germany

fYear

2015

fDate

25-28 Jan. 2015

Firstpage

1

Lastpage

3

Abstract

A miniaturized transmission-line sensor based on a coplanar waveguide with increased sensitivity is used to characterize living and dead CHO-K1 cells in suspension. The biological samples are guided across the sensor in a microfluidic channel which is fabricated using microsystems technology. The broadband sensor is used between 850MHz and 40 GHz to detect the permittivity of liquid samples. The contrast between living and dead cells in suspension is significant despite a very small sampling volume.

Keywords

bioMEMS; bioelectric phenomena; cellular biophysics; coplanar waveguides; microchannel flow; microsensors; permittivity; suspensions; CHO-K1 cells; biological samples; broadband dielectric characterization; coplanar waveguide; frequency 850 MHz to 40 GHz; liquid samples; microfluidic channel; microsystems technology; miniaturized transmission-line sensor; permittivity; sampling volume; suspension; Dielectrics; Liquids; Microwave theory and techniques; Permittivity; Sensors; Suspensions; Transmission line measurements; Biological cells; microfluidics; microwave measurement; permittivity; transmission line measurements;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS), 2015 IEEE Topical Conference on

Conference_Location

San Diego, CA

Type

conf

DOI

10.1109/BIOWIRELESS.2015.7152127

Filename

7152127