Title :
Broadband dielectric characterization of CHO-K1 cells using miniaturized transmission-line sensor
Author :
Meyne, Nora ; Fuge, Grischa ; Hemanth, Suhith ; Trieu, Hoc Khiem ; An-Ping Zeng ; Jacob, Arne F.
Author_Institution :
Inst. fur Hochfrequenztech., Tech. Univ. Hamburg-Harburg, Hamburg, Germany
Abstract :
A miniaturized transmission-line sensor based on a coplanar waveguide with increased sensitivity is used to characterize living and dead CHO-K1 cells in suspension. The biological samples are guided across the sensor in a microfluidic channel which is fabricated using microsystems technology. The broadband sensor is used between 850MHz and 40 GHz to detect the permittivity of liquid samples. The contrast between living and dead cells in suspension is significant despite a very small sampling volume.
Keywords :
bioMEMS; bioelectric phenomena; cellular biophysics; coplanar waveguides; microchannel flow; microsensors; permittivity; suspensions; CHO-K1 cells; biological samples; broadband dielectric characterization; coplanar waveguide; frequency 850 MHz to 40 GHz; liquid samples; microfluidic channel; microsystems technology; miniaturized transmission-line sensor; permittivity; sampling volume; suspension; Dielectrics; Liquids; Microwave theory and techniques; Permittivity; Sensors; Suspensions; Transmission line measurements; Biological cells; microfluidics; microwave measurement; permittivity; transmission line measurements;
Conference_Titel :
Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS), 2015 IEEE Topical Conference on
Conference_Location :
San Diego, CA
DOI :
10.1109/BIOWIRELESS.2015.7152127
