Title :
Bending effect on magnetoresistive silicon probes
Author :
Valadeiro, J. ; Amaral, J. ; Gaspar, J. ; Leitao, D.C. ; Silva, A.V. ; Cardoso, S. ; Freitas, P.
Author_Institution :
INESC-MN, Lisbon, Portugal
Abstract :
Mapping the brain´s activity can be done either with non-invasive techniques (e.g. magnetic resonance, electro/magnetoencephalography), or by studies performed in-vivo/vitro at the cell level usually using small-sized electrodes (10 μm) to measure local potentials. Probing locally the neuronal magnetic fields created by the synaptic currents can be done with magnetrodes [1], which combine high sensitive magnetoresistive sensors (spinvalve, SV) with micro-machined Si probes. The SV sensors were deposited by ion beam with the following stack: Ta 2/Ni80Fe20 3.5/Co80Fe20 2.3/Cu 2.3/Co80Fe20 2.3/Mn76Ir24 8/Ta 5/Ti10W90N 15 (thickness in nm). The sensors were patterned in arrays of N=952 elements (350 μm2 each) connected in series, in order to bring the detectivity levels below pTesla. This strategy was already demonstrated viable when the device footprint is not an issue for the considered application [2]. The sensors were incorporated in micromachined thin Si needles with well defined tip angle and intrinsic bending capability. This approach induces a minimum damage when inserting the probes within the brain tissues and enhances the sensors proximity to the signal sources, with a spatial resolution unmatched by any of the competing neuroscience tools. The Si needles were defined [3] with a length of 11.3 mm and width of 1 mm [Figure 1]. The separation between the tip of the needle and the array middle point was set in 3.5 mm. In the fabrication process three Si substrates (Young modulus E=1.3×1012 dyn/cm2) with different thicknesses are used: (i) 700 μm, (ii) 400 μm and (iii) 50 μm, being the later a Silicon-On-Insulator (SOI) wafer. The impact of bending in the sensor transfer curve and noise level were investigated, aiming at optimizing the detectivity limits under conditions si- ilar to those implemented in the in-vivo experiments.
Keywords :
Young´s modulus; bending; biomagnetism; brain; magnetoresistive devices; silicon; Si; Silicon-On-Insulator wafer; Young modulus; a spatial resolution; bending effect; brain activity mapping; brain tissues; cell level; device footprint; ion beam; magnetoresistive silicon probes; magnetrodes; neuronal magnetic fields; noise level; sensor transfer curve; synaptic currents; tip angle; Magnetic field measurement; Magnetic sensors; Magnetostriction; Needles; Probes; Silicon;
Conference_Titel :
Magnetics Conference (INTERMAG), 2015 IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4799-7321-7
DOI :
10.1109/INTMAG.2015.7156768