A microwave reconfigurable dielectric-based glucose sensor with 20 mg/dL sensitivity at sub-nL sensing volume in CMOS

Author

Jun-Chau Chien ; Erh-Chia Yeh ; Lee, Luke P. ; Anwar, Mekhail ; Niknejad, Ali M.

Author_Institution

Univ. of California, Berkeley, Berkeley, CA, USA

fYear

2015

fDate

17-22 May 2015

Firstpage

1

Lastpage

4

Abstract

In this paper, a reconfigurable dielectric-based glucose sensor is implemented in 65nm CMOS. Measurements over wide concentration range are achieved through frequency detection while high sensitivity is realized by the interferometer architecture. A sensitivity limit of 20 mg/dL is measured with 0.18-nL of sensing volume. Four independent sensing channels operating from 6 - 30 GHz facilitates broadband characterization of the glucose medium.

Keywords

CMOS integrated circuits; biomedical equipment; dielectric devices; interferometers; microwave detectors; nanomedicine; nanosensors; sugar; CMOS; broadband characterization; frequency 6 GHz to 30 GHz; frequency detection; independent sensing channels; interferometer architecture; microwave reconfigurable dielectric-based glucose sensor; sensitivity limit; size 65 nm; sub-nL sensing volume; CMOS integrated circuits; Chemicals; Frequency measurement; Microstrip; Sensors; Spectroscopy; Sugar; dielectric; glucose; injection-locked oscillators; interferometer; microfluidic; permittivity;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave Symposium (IMS), 2015 IEEE MTT-S International

Conference_Location

Phoenix, AZ

Type

conf

DOI

10.1109/MWSYM.2015.7167141

Filename

7167141