• DocumentCode
    727790
  • Title

    On the robustness of SNPs filtering using computational intelligence

  • Author

    Zonovelli, Bruno ; Hasenclever Borges, Carlos Cristiano ; Arbex, Wagner

  • Author_Institution
    Comput. Sci. Dept., Fed. Univ. of Juiz de Fora, Juiz de Fora, Brazil
  • fYear
    2015
  • fDate
    17-20 June 2015
  • Firstpage
    1
  • Lastpage
    6
  • Abstract
    This work uses a filter based on neural networks to verify the mismatches in two Arabidopsis thaliana germplasm. Aiming to demonstrate the robustness and adaptability of the filter it will be applied in a reuse model context. The neural network filter previously defined and performed using the genome of an animal of the species Bos Taurus is used maintaining the main parameterization pre-defined to identify the SNPs on the mismatches detected in the reassembled germplasm. The experiments with the adapted filter in the new genome indicate that the quality and level of SNPs detection are preserved despite of the lack of a training process for this specific data.
  • Keywords
    bioinformatics; genomics; neural nets; Bos Taurus; SNP filtering; SNP identification; animal genome; arabidopsis thaliana germplasm; bioinformatics; computational intelligence; neural network filter; reuse model context; Bioinformatics; Bovine; Filtering; Genomics; Robustness; Software; Training; Bioinformatics; Computational Intelligence; Genomic DNA; Neural Network; NeuroSNP; SNP Filtering;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information Systems and Technologies (CISTI), 2015 10th Iberian Conference on
  • Conference_Location
    Aveiro
  • Type

    conf

  • DOI
    10.1109/CISTI.2015.7170411
  • Filename
    7170411