• DocumentCode
    731737
  • Title

    Capillary driven and volume-metred blood-plasma separation

  • Author

    Lenk, G. ; Hansson, J. ; van der Wijngaart, W. ; Stemme, G. ; Roxhed, N.

  • Author_Institution
    KTH R. Inst. of Technol., Stockholm, Sweden
  • fYear
    2015
  • fDate
    21-25 June 2015
  • Firstpage
    335
  • Lastpage
    338
  • Abstract
    Blood plasma samples are widely used in clinical analysis but easy-to-use sampling methods for defined volumes are lacking. We introduce the first capillary driven microfluidic device that separates a specific volume of plasma from a blood sample of unknown volume. The input to the device is a small amount of whole blood in the range of 30-60 μl which results in a 4 μl isolated plasma sample within 3 minutes, available for subsequent processing and/or analysis, as demonstrated by collecting the sample in a paper substrate.
  • Keywords
    bioMEMS; blood; capillarity; microfluidics; capillary driven blood-plasma separation; capillary driven microfluidic device; isolated plasma sample; volume-metred blood-plasma separation; Blood; Filtration; Microchannels; Microfluidics; Plasmas; Testing; Valves; Blood plasma separation; Microfluidic; Point-of-care; Volume metering;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers - 2015 18th International Conference on
  • Conference_Location
    Anchorage, AK
  • Type

    conf

  • DOI
    10.1109/TRANSDUCERS.2015.7180929
  • Filename
    7180929