• DocumentCode
    732469
  • Title

    Label-free imaging of single neuron activities by stimulated Raman scattering

  • Author

    Delong Zhang ; Hyeon Jeong Lee ; Pei-Yu Shih ; Drenan, Ryan E. ; Ji-Xin Cheng

  • Author_Institution
    Weldon Sch. of Biomed. Eng., Purdue Univ., West Lafayette, IN, USA
  • fYear
    2015
  • fDate
    10-15 May 2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We report the observation of single neuron activities by spectral focusing stimulated Raman scattering (SRS) microscopy. Changes in SRS signal intensity in live neurons correlate to action potentials indicated by fluorescent calcium indicator.
  • Keywords
    calcium; cellular biophysics; fluorescence; optical focusing; optical microscopy; stimulated Raman scattering; Ca; SRS signal intensity; fluorescent calcium indicator; label-free imaging; single neuron activities; spectral focusing stimulated Raman scattering microscopy; Calcium; Fluorescence; Image resolution; Microscopy; Neurons; Raman scattering;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2015 Conference on
  • Conference_Location
    San Jose, CA
  • Type

    conf

  • Filename
    7182901