• DocumentCode
    736883
  • Title

    Identification of Pentostain Isomers

  • Author

    Wang, C.H. ; Gao, L.P. ; Wang, X.P.

  • fYear
    2015
  • fDate
    13-14 June 2015
  • Firstpage
    538
  • Lastpage
    540
  • Abstract
    Aiming at improve the pentostatin quality control in cGMP production, and the identification method of Pentostain isomers was provided based on the experiment in this papers. These isomers were synthesized and then hydrolyzed into diamine but its chiral centre remains unchanged. The hydrolyzates of isomers are compared with pentostatin hydrolyzate on chiral HPLC and then the chiral configurations of these isomers were identified.
  • Keywords
    Chemistry; Detectors; Inhibitors; Mobile communication; Quality control; Workstations; Chiral-LC; Hydrolyzation; Isomer; Pentostatin; Pre-LC;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Measuring Technology and Mechatronics Automation (ICMTMA), 2015 Seventh International Conference on
  • Conference_Location
    Nanchang, China
  • Print_ISBN
    978-1-4673-7142-1
  • Type

    conf

  • DOI
    10.1109/ICMTMA.2015.136
  • Filename
    7263629
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=736883