DocumentCode
738383
Title
Aptamer and graphene-based electrochemical biosensor for dopamine determination with high sensitivity and selectivity
Author
Jiao, Liangbao ; Lu, Guo-Quan ; Zhang, Chenghui ; Yuan, Yuan ; Wang, Jiacheng ; Zhang, Qi ; Li, Peng
Author_Institution
Department of Laboratory Medicine, XinXiang Medical University, XinXiang 453003, People´s Republic of China
Volume
8
Issue
12
fYear
2013
fDate
12/1/2013 12:00:00 AM
Firstpage
903
Lastpage
905
Abstract
Dopamine is a kind of neurotransmitter. The abnormalities in dopamine metabolism may lead to various psychiatric and neurodegenerative diseases. Thus, fast and accurate detection of dopamine is urgently needed. Presented in this Letter is a convenient and cost-effective electrochemical method for the detection of dopamine based on aptamer and graphene. The specific recognition between dopamine and the RNA aptamer allows high selectivity, and the excellent electronic properties of graphene nanosheets ensure the high sensitivity of this biosensor.
fLanguage
English
Journal_Title
Micro & Nano Letters, IET
Publisher
iet
ISSN
1750-0443
Type
jour
DOI
10.1049/mnl.2013.0626
Filename
6750532
Link To Document