Title :
Sensitivity Enhancement of Surface Plasmon Resonance Imaging Using Periodic Metallic Nanowires
Author :
Byun, Kyung Min ; Shuler, Michael L. ; Kim, Sung June ; Yoon, Soon Joon ; Kim, Donghyun
Author_Institution :
Dept. of Biomed. Eng., Cornell Univ., Ithaca, NY
fDate :
6/1/2008 12:00:00 AM
Abstract :
A nanowire-mediated surface plasmon resonance (SPR) imaging is numerically investigated for enhanced sensitivity. The results calculated by rigorous coupled-wave analysis present that interplays between localized surface plasmons and surface plasmon polaritons contribute to sensitivity enhancement. Compared to conventional thin film-based SPR imaging measurement, an optimal nanowire structure can provide sensitivity enhancement by 3.44 times as well as highly linear detection property for quantification of surface reactions of interests. This paper demonstrates the potential and limitation for a highly sensitive, label-free, and real-time SPR imaging sensor based on periodic metallic nanowires.
Keywords :
biochemistry; biomedical optical imaging; biosensors; image sensors; nanowires; optical materials; optical sensors; polaritons; surface chemistry; surface plasmon resonance; label-free real-time imaging sensor; localized surface plasmons; nanowire-mediated SPR imaging; periodic metallic nanowires; rigorous coupled-wave analysis; sensitivity enhancement; surface plasmon polaritons; surface plasmon resonance imaging; surface reaction quantification; Biomedical engineering; Biomedical measurements; Biosensors; Fluorescence; Nanoparticles; Nanowires; Optical imaging; Plasmons; Resonance; Wavelength measurement; Imaging; metallic nanowires; optical sensors; sensitivity; surface plasmons;
Journal_Title :
Lightwave Technology, Journal of
DOI :
10.1109/JLT.2008.922182
