Title :
Molecular Imaging of Cancer: Applications of Magnetic Resonance Methods
Author :
Gimi, Barjor ; Pathak, Arvind P. ; Ackerstaff, Ellen ; Glunde, Kristine ; Artemov, Dmitri ; Bhujwalla, Zaver M.
Author_Institution :
Cellular Molecular Imaging Center, Johns Hopkins Univ., Baltimore, MD, USA
fDate :
4/1/2005 12:00:00 AM
Abstract :
Cancer is a complex disease exhibiting a host of phenotypic diversities. Noninvasive multinuclear magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) provide an array of capabilities to characterize and understand several of the vascular, metabolic, and physiological characteristics unique to cancer. The availability of targeted contrast agents has widened the scope of MR techniques to include the detection of receptor and gene expression. In this paper, we have highlighted the application of several MR techniques in imaging and understanding cancer.
Keywords :
biomedical MRI; cancer; molecular biophysics; cancer; contrast agents; gene expression; magnetic resonance spectroscopic imaging; molecular imaging; noninvasive multinuclear magnetic resonance imaging; phenotypic diversities; receptor expression; vascular imaging; Cancer; Content addressable storage; Diseases; Gene expression; Magnetic resonance; Magnetic resonance imaging; Molecular imaging; Probes; Protons; Spectroscopy; Cancer; magnetic resonance imaging (MRI); magnetic resonance spectroscopic imaging (MRSI); metabolism; molecular imaging; receptor expression; vascular imaging;
Journal_Title :
Proceedings of the IEEE
DOI :
10.1109/JPROC.2005.844266
